Therapeutic Modulation of the Immune Response in Arrhythmogenic Cardiomyopathy
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چکیده
منابع مشابه
The Immune Response and Its Therapeutic Modulation in Bronchiectasis
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A rrhythmogenic cardiomyopathy (AC) is an inherited heart muscle that affects ≈1 to 2 in 5000 individuals and accounts for 15% to 25% of cases of sudden cardiac death in patients <35 years. 1 The cardiomyopathy is characterized by risk for lethal ventricular arrhythmias, ventricular enlargement and dysfunction, and fibro-fatty replacement of cardio-myocytes. Curiously, the disease often disprop...
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A 53-year-old white man was identified through family screening as having arrhythmogenic right ventricular cardiomyopathy caused by a frameshift mutation in the desmoplakin gene (DSP S1015fsX1017). Direct questioning revealed a previously undisclosed history of palpitations. The electrocardiogram (ECG) showed anterolateral T-wave inversion (Figure 1). Holter monitoring detected an asymptomatic ...
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ژورنال
عنوان ژورنال: Circulation
سال: 2019
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.119.040676